产品货号:
Z10267
中文名称:
ADAM17抗体
英文名称:
Anti-ADAM17 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ADAM17 Antibody |
指标别名 | ADAM 17;ADAM17;CD156b;cSVP;Snake venom like protease;TACE;TNF alpha convertase;TNF alpha converting enzyme |
克隆性 | Polyclonal |
检验物种 | human,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | ADAM17 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-TACE antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TACE.The immunogen is located within the last 50 amino acids of TACE. |
计算分子量 | 93kDa |
成分 | TACE Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TACE Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Tumor-necrosis factor-alpha is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death.TNF-汐is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-汐.TNF-汐converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately.TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease).TACE also processes other cell surface proteins,including TNF receptor,TGFalpha,the L-selectin adhesion molecule,and alpha-cleavage of amyloid protein precursor (APP).TACE mRNA is expressed in a variety of human and murine tissues.TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. |
Uniprot ID | P78536 |
基因名全称 | ADAM metallopeptidase domain 17 |
蛋白名全称 | ADAM metallopeptidase domain 17 |
推荐稀释比 | WB:0.25~2μg/mL;ICC:10μg/mL;IF:10μg/mL.Antibody validated:Western Blot in human and rat samples;Immunocytochemistry in human samples;and Immunofluorescence in human and rat samples.All other applications and species not yet tested. |
相关搜索:ADAM17抗体,ADAM17多抗,Anti-ADAM17 Antibody